Mammals primarily use Nucleotide Excision Repair (NER) to erase large DNA lesions like those caused by UV radiation. Light, the environment, and several DNA-based cancer chemotherapeutic drug users.
NER deficiencies linked to the genetic condition Xeroderma pigmentosum, which is incredibly risky for developing skin cancer. The fundamental distinction between base excision repair and nucleotide excision repair is that base excision repair only corrects damaged bases, which are non-bulky lesions, whereas nucleotide excision repair corrects bulky DNA adducts by removing short single-stranded DNA segments. Damage recognition, subunit assembly, dual incisions that result in excision of the damage-containing oligomer, resynthesis to fill in the gap and ligation to regenerate an intact molecule are the basic mechanisms of nucleotide excision repair.
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omip-069: forty-color full spectrum flow cytometry panel for deep immunophenotyping of major cell subsets in human peripheral blood
For detailed immunophenotyping of the primary cell subsets found in human peripheral blood, a 40-color flow cytometry-based panel was created.
What is 40-color flow cytometry?When several different types of testing must be conducted on a single sample or timepoint, sample availability is frequently constrained, especially in the case of clinical trial material. In addition to providing a more thorough assessment of the immune system, maximizing the quantity of information that can be gleaned from a single sample helps to solve the problem of restricted sample availability. CD4 T cells, CD8 T cells, regulatory T cells, T cells, NKT-like cells, B cells, NK cells, monocytes, and dendritic cells are all identified in the panel.Learn more about the Flow cytometry with the help of the given link:
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What general information about the serengeti do we need to research to further investigate the causes for the changes in the african buffalo population?
Water is what we need to research to further investigate the causes for the changes in the african buffalo population since there is lack of water in serengeti.
Aside from water here are some other factors that are affecting the african buffalo population:
High biodiversity exists.Varying terrainLow predator density relative to prey densityAnimals called buffalo reside in the Serengeti. From 1960 to 1975, the buffalo population significantly grew. Tanzania is the home of the Serengeti. It is a sizable space. The Serengeti is home to a wide variety of species. Photographs are being taken of them by researchers. It has a lot of large plant-eating creatures for its size. There are numerous biodiversities there.
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What is true about the development of fish and birds?
A.
Both fish and birds contain gill slits as early embryos, and both contain gills in later development.
B.
Gill slits develop into gills in birds, but as fish develop they lose their gill slits.
C.
Gill slits develop into gills in fish, but as birds develop they lose their gill slits.
D.
Both fish and birds contain gill slits as early embryos, and neither contain gills in later development.
Answer:
A
Explanation:
correct me if i'm wrong
Which term describes DNA sequences that code for proteins
- genome
- gene
- regulatory sequences
- non-coding regions
Explanation:
Gene
A segment of a DNA molecule (a sequence of bases) that codes for a particular protein and determines the traits (phenotype) of the individual. A gene is the basic unit of heredity in a living organism.
I need to know a hypothesis
The iv
Control group
E group
Do
Constants
ldentification of a disease resistance locus in arabidopsis that is functionally homologous to the rpg7 locus of soybean
It was identified that a disease resistance locus in Arabidopsis is functionally homologous to the rpg1 locus of soyabean.
How was disease resistant locus identified in Arabidopsis?Using an avirulence gene that was previously cloned from a pathogen that does not affect Arabidopsis, the new disease resistance locus RPS3 in that plant was discovered. Pseudomonas syringae pv. tomato strain that is virulent on Arabidopsis was transformed with the avrB avirulence gene from the soybean pathogen, and conversion to avirulence was tested on Arabidopsis plants. On most Arabidopsis ecotypes, but not all, the avrB gene was avirulence active. Of the 53 ecotypes that were tested, eight were susceptible and 45 were resistant to a P. syringae pv. tomato strain that carried avrB. Crosses between the susceptible ecotype Bla-2 and the resistant ecotype Col-0 were used to study the transmission of this resistance. The ratio of resistant to susceptible F2 plants from this cross was almost 3:1, showing that ecotype Col-0's solitary dominant locus, RPS3, controls resistance to P. syringae that expresses avrB. RPS3 was located on chromosome 3 near markers M583 and G4523 and or = 1 cM from RPM1, another disease resistance locus, using RFLP analysis. The locus RPG1 in soybean regulates resistance to P. syringae strains that possess avrB. As a result, RPG1 and RPS3 both provide resistance to avrB-specific diseases, raising the possibility that these genes are homologs.
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The correct question is Identification of a disease resistance locus in Arabidopsis that is functionally homologous to the RPG1 locus of soybean
lung tissues make the
lung organ,____
tissue make the pancreas
organ
Lung tissues make the lung organ, exocrine tissue makes the pancreas organ.
Explanation:Almost all of the pancreas (95%) consists of exocrine tissue that produces pancreatic enzymes for digestion. The remaining tissue consists of endocrine cells called islets of Langerhans. These clusters of cells look like grapes and produce hormones that regulate blood sugar and regulate pancreatic secretions. The pancreas is invested by a very thin connective tissue capsule and divided into lobules, which in turn are formed from dense accumulations of exocrine glands that often surround islets of Langerhans.
Epithelial cells that are adapted for absorption usually have ________ at their free surface.
Answer:
Epithelial cells that are adapted for absorption usually have ___Microvilli_____ at their free surface.
conifer leaves are generally thin and needle-like, while seeds are contained in cones. conifers include blank and blank
Conifer leaves are generally thin and needle-like, while seeds are contained in cones. Conifers include pine and cedar.
One of the most familiar and particular characteristics of this group of plants is that they are 'evergreen plants'.
They belong to the class of gymnosperm plants and exhibit secondary growth properties. Outer appearance shows that they are straight, long and pointy end plants having woody stems and trunks.
Their bark has horizontal round circles and their internal structure becomes complex as they grow older.
Moreover, the trees of this group are also covered with blades, scales and wedges along with a waxing coating that prevents water loss from the leaves.
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Please Help due soon.
Explanation:
marshes and swamps.
answer
anaphylaxis caused by stinging insects is typically an allergic reaction to rather than the bite or sting itself.
Anaphylaxis caused by stinging insects is typically an allergic reaction to the injected poison, irritating toxin, and deadly venom rather than the bite or sting itself. The correct answer is option(D)i.e, All of these answers are correct.
Anaphylaxis can be fatal if untreated or improperly treated. Even if your symptoms disappear pretty quickly, they may return a few hours later, worsen, and become more challenging to cure.
People who have allergies typically experience mild to moderate symptoms, such as watery eyes, a runny nose, or a rash. Anaphylaxis, a serious allergic reaction that can be fatal, can however occasionally result from exposure to an allergen. When too many chemicals are released at once, shock results, which is a severe reaction
The most frequent triggers within these groups were wasp and bee stings (n = 1460 and 412, respectively), legumes (n = 241), animal proteins (n = 225), and analgesics (n = 277). In children, peanuts, cow milk, and hen's eggs were the most common food allergens to cause anaphylaxis; in adults, it was wheat and shellfish. When you have anaphylaxis, your immune system releases a rush of chemicals that can put you in shock and cause your blood pressure to drop and your airways to constrict.
The complete question is:
Anaphylaxis caused by stinging insects is typically an allergic reaction to ____________ rather than the bite or sting itself.
A. injected poison
B. irritating toxin
C. deadly venom
D. All of these answers are correct
rotein synthesis is an essential part of cellular metabolism, and it requires the involvement of a number of molecules, structures, and organelles. list the molecules, structures, and organelles in the order that enables protein synthesis. start with the instructions that encode a protein, and end with the structure through which a protein leaves the cell.
According to the given statement the correct order is
DNA ⇒ RNA ⇒ Ribosomes ⇒ Endocytic reticulum in rough ⇒ Golgi apparatus ⇒ Plasma layer ⇒ Protein Leaves the Cell
What is Ribosome?At a ribosome, an intercellular structure made of both RNA and protein, the process of making proteins happens in a cell. The messenger RNA (mRNA) sequence is processed by the ribosome, which translates the gene sequence into a specific string of amino acids that form extended chains and fold to make proteins.
What roles do ribosomes function?Ribosomes' two major purposes are peptide bond formation and message decoding. These two tasks are carried out by the two large, unequal-sized ribonucleoprotein particles (RNPs) called as the ribosomal subunits. A variety of ribosomal proteins and one or more ribosomal RNAs (rRNAs) make up each subunit (r-proteins)
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Provisions in the tax law that promote energy conservation and more use of alternative (nonfossil) fuels can be justified by?
Provisions in the tax law that promote energy conservation and more use of alternative nonfossil fuels can be justified by economic and social considerations. The developing countries are facing formidable challenges when they are attempted to establish an efficient system of taxes.
Provisions in the tax law that promote energy conservation are clearly justified by particular social type consideration since the tax credits for clean energy and other provisions were included in the bill that would increase the production of energy at home and will accelerate the innovation of energy abroad.
Additionally, by the investment in disadvantaged communities, projects will be prioritized that can reutilize retired infrastructure of fossil fuel and will employ the displaced workers as it included the particular incentives for the practices of climate-smart agriculture, the IRA would make meaningful progress as it will be forwarding towards a fair, equitable as well as the economic type of clean energy transition.
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what happens to the cell of a animal as you grow
Answer:
the cells divide
Explanation:
firs cell divide into 2 daughter cells and then to 4 and then it keeps on going
In addition to sunlight, which factor would need to be added to make this a stable ecosystem?
A. Predators
C. Decomposers
E. Carnivores
B. Prey
D. Herbivores
Answer:
B. Prey
Explanation:
The amount of prey dictates how much food there is and how much energy for each creature.
Enzymes act as_______________ in the body and help ______________ the metabolic processes within the cell. locks, slow down immune factors, protect chemical catalyst, speed up gatekeepers, monitor
Enzymes act as organic catalyst in the body and help in the speed up the metabolic processes within the cell.
Enzymes- An enzyme is a type of biological catalyst that is typically always a protein. It quickens a certain chemical reaction inside the cell. Throughout the procedure, the enzyme is continually used and is not lost.
Amylase, for instance, supports the transformation of carbs into sugars in saliva.
Metabolic Process- Metabolic activities in the body's cells that turn food into energy are referred to as metabolism. Our bodies need this energy in order to move, think, and develop. Specific proteins in the body control the chemical reactions involved in metabolism.
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The genes for the traits that mendel worked with are either all located on different chromosomes or behave as if they were. How did this help mendel recognize the principle of independent assortment?.
The genes for the traits that Mendel worked with are either all located on different chromosomes or behave as if they were. This helps Mendel recognize the principle of independent assortment as otherwise, his dihybrid crosses would not produce a 9 : 3 : 3: 1 ratio of F2 phenotypes in a generation.
Mendel discovered the principle of independent assortment after performing a specific dihybrid cross as it is between plants that had any two traits which include seed color and pod color which are different from one another. Whenever these plants were allowed to pollinate themselves by self-pollination, he then noticed that the same ratio that is 9:3:3:1 appeared among the offspring produced also.
The Principle of Independent Assortment determines how different types of genes get independently separate from each another when the development of reproductive cells takes place. The Independent assortment of genes as well as their corresponding traits was actually first observed by Gregor Mendel during his genetics studies in pea plants.
This principle in genetics otherwise depicts as those hereditary units occurring in pairs that are separated during the formation of gametes so that each and every gamete receives some trait but only by one member of a pair. It is also called the law of segregation.
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based on the matrix, which tree represents the most parsimonious explanation of relatedness among these species?
Based on the matrix Phylogeny 2 tree represents the most parsimonious explanation of relatedness among these species
The study of relationships and the evolutionary history of various groupings of species is known as phylogeny. The goal of phylogeny is to reconstruct the evolutionary course of all species on Earth. It is based on the phylogenetic theory, which holds that all living things descended from a single common ancestor. A phylogenetic tree is a visual representation of how species are related to one another. The comparison of genetic and anatomical similarities shows that relationships are based on shared traits.
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Read and answer the questions!
Please I need help ASAP!
Will give brainlist to the first right person!!!
Questions
1. What signs and symptoms did Greg exhibit when he was in the house?
2. Was Mrs. Myron correct when she said that Greg was dehydrated? Which signs and symptoms are consistent
with this notion?
3. Explain how each sign or symptom can be created by dehydration.
4. Mrs. Myron thought that it was not necessary to seek medical treatment. Do you think she was correct?
1. The signs and symptoms Greg exhibited at the home were dizzy thirsts, weakness, and poor skin turgor.
2. Yes, Mrs. Myron was correct when she said that Greg was dehydrated. Dizziness, thirst, weakness, and poor skin turgor. Weakness and dizziness occur as there is reduced blood flow to the brain and other organs due to dehydration. Dehydration stimulates the thirst center of the brain and causes thirst.
3. Dehydration skin means skin lacking water. This is when we pinch the skin, due to poor skin turgor, it takes a longer time for the skin to return back to its normal position.
4. Heat stess heat exhaustion or heat stroke can be treated easily in the following ways Get out of the heat quickly and get into, lying down and elevating your legs to get blood flow to the heart, take off any extra or tight clothing, apply cool towels to the skin or take a cool bath. This will help to regulate the internal body temperature. drink fluids if the fever not getting down, or the patient goes into seizure, shock, and faints or stops breathing, immediate professional intervention becomes necessary.
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incorporating target-mediated drug disposition in a minimal physiologically-based pharmacokinetic model for monoclonal antibodies
Incorporating target-mediated drug disposition in a minimal physiologically-based pharmacokinetic model for monoclonal antibodies is a research paper by Yanguang Cao and William J Jusko.
What is the abstract?The term "target-mediated drug disposition" (TMDD) refers to the nonlinear pharmacokinetics (PK) of medicines whose distribution and/or clearance are influenced by their targets due to high affinity and/or capacity. For this reason, TMDD in monoclonal antibodies (mAb) is frequently documented. A generic method for assessing mAbs PK and forecasting mAb interstitial concentrations in two groups of tissues is provided by minimal physiologically-based pharmacokinetic models (mPBPK), which account for the specific PK behaviors of mAb. This study examined the viability of including TMDD in mPBPK models to take target-binding in plasma (cTMDD) or interstitial fluid (ISF) into consideration (pTMDD). The pTMDD model's dose-related signature profiles show a parallel early decay phase, in contrast to the cTMDD model, which shows a quicker initial decline at low doses.
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Evidence 2: A tool impression has been found at the crime scene. Lab technicians have analyzed the impression and have determined that it is from a crowbar that has a chipped right corner of the beak (the split end). A crowbar found at the suspect's home has a similar chip in the right corner of the beak. Is this class or individual?
A crowbar is a metal bar tool with flattened ends at each end, generally with a small crack to aid remove nails or pushing two materials or items apart. It is also referred to as a wrecking bar, gorilla bar, pinch bar, or a pry bar.
Crowbars, pinch bars, and pry bars are hand tools used to pry two items apart. Their flattened, angled end functions as a lever, letting you exert a substantial amount of force between objects.A lever is something like a crowbar.In a lever, the load force is on the opposite side from where a person pushes or pulls and is applied to the side of the thing we are trying to lift or pry apart.Learn more about tool impression here:
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IS NEEDED ASAP PLEASE HURRY
The number of snails in a given Alabama creek bed by each of 30 segments of the creek is as follows:
32, 6, 21, 10, 8, 11, 12, 36, 17, 16, 15, 18, 40, 24, 21, 23, 24, 24, 29, 1, 4, 9, 32, 23, 40, 15, 29, 25, 33, 20
What is the median number of snails of the 30 segments of this Alabama creek?
Question 6 options:
24
23
21
Answer: Median is 21
Explanation:
A bus starts from rest and accelerates to 14 m/s in 4 s. What is the average acceleration
of the bus?
The average acceleration of the bus, given it accelerated from rest is 3.5 m/s²
How do i determine the average acceleration?We know that acceleration is defined as the rate of change of velocity which time.
a = (v – u) / t
Where
a is the acceleration v is the final velocity u is the initial velocity t is the timeWith the above formula, we can obatin the average acceleration as follow:
Initial velocity (u) = 0 m/sFinal velocity (v) = 14 m/sTime (t) = 4 sAverage acceleration (a) =?a = (v – u) / t
a = (14 – 0) / 4
a = 14 / 4
a = 3.5 m/s²
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i know that my organism is 2um, if i wanted to view my organism so it appears to be 2mm, what objective lens would i want to use?
40X Objective Lens will get in use.
Objective Lens- An essential component of the microscope's optics is the objective lens. The sample, specimen, or item being examined is situated close to the microscope's objective. It plays a crucial part in imaging since it creates the initial magnified picture of the sample.
Specimen- A special instance of a certain sort or species of an animal, plant, mineral, etc. utilized for research or display.
Microscope- A microscope is a tool that magnifies a small object's picture to reveal details that the unaided eye is unable to see. The most common kind of microscope is the optical microscope, which uses visible light that has been focused by lenses.
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Dna sequences in many human genes are very similar to the sequences of corresponding genes in chimpanzees. The most likely explanation for this result is that.
Since the two species are so closely related, human and chimp DNA is remarkably similar. From a single progenitor species that existed six or seven million years ago, humans, chimpanzees, and bonobos all descended. Their DNA, which is passed down from generation to generation, changed as humans and chimpanzees eventually evolved from a shared ancestor.
The latest DNA research reveals that humans, chimpanzees, and gorillas all descended from a single ancestor about 10 million years ago when combined with previously found remains. Then, according to the latest findings, humans, and chimpanzees originated from that lineage around 6 million years ago.The Hominidae is a family of organisms that includes living humans, chimpanzees, gorillas, orangutans, and their extinct ancestors. According to comparisons of morphology and DNA, scientists largely concur that, among the extant animals in this group, humans are most closely related to chimpanzees.Different species with comparable architecture may be homologous (shared by ancestry) or analogous (shared due to similar selective pressures). Similarities at the molecular level are proof that life has a common ancestor. Comparing DNA sequences can reveal the relationships between various species.Learn more about DNA sequences here:
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Where does energy in the sugar molecules made by photosynthesis come from?
Answer: the sun
Explanation: during the process of photosynthesis, cells use carbon dioxide and energy from the sun to make sugar molecules and oxygen. These sugar molecules are the basis for more complex molecules made by the photosynthetic cell, such as glucose.
In thick skin, what do the Dermal Papilla produce?
In thick skin, the dermal papilla produce the hair shaft.
What is a dermal papilla?The dermal papilla is a finger-shaped structure that will be found in an area where the dermis interdigitates with the epidermis. In the dermal papillae we will find blood vessels that will nourish the hair follicles, carrying nutrients to the deepest layers of the epidermal cells.
The dermal papillae are found in the outermost layer of the dermis, called the papillary dermis. Having a role in the formation and growth of hair.
Therefore, we can confirm that in thick skin, the dermal papilla produce the hair shaft.
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Trey wrote a few steps to describe how carbon circulates between the atmosphere and living organisms.
Step 1. Carbon enters the atmosphere as carbon dioxide from respiration and the burning of fossil fuels.
Step 2. Plants absorb carbon dioxide in the air and use it to make their own food using photosynthesis.
Step 3. Plant-eating animals consume the carbon stored in plants.
If step 2 is removed, which statement best describes the effects of this missing step on the carbon cycle? (2 points)
Less carbon is stored in the ground for long-term storage.
There is a decrease in the amount of carbon stored in the air.
More carbon is stored in plants instead of the air.
Animals consume foods without stored carbon.
If step 2 is removed, the statement which best describes the effects of this missing step on the carbon cycle is less carbon is stored in the ground for long-term storage and is denoted as option A.
What is Photosynthesis?This is referred to as the process in which green plants manufacture food in the presence of sunlight and use certain compounds such as carbon dioxide, water etc.
Plants are primarily responsible for absorbing carbon dioxide from the air and storing it in the form of Soil organic carbon in the ground which is why less carbon will be stored in the ground for long-term storage when plants don't absorb carbon dioxide in the air and use it to make their own food using photosynthesis.
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Plants make sugar through photosynthesis, but they don't need that sugar
for anything. True or false
Answer:
False
Explanation:
Answer:
False!
Explanation:
They need it to make glucose!
The hormone that plays a pivotal role in setting the metabolic rate and thus impacting body temperature is.
Thyroxine hormone is a hormone that plays an important role in regulating metabolic rate and hence body temperature.
Thyroxine is a hormone that is important in regulating body's metabolism and thus body temperature. Because it is released into the bloodstream by the thyroid gland, this hormone is also known as thyroid hormone. Thyroxine (T4) is the inactive form of thyroid hormone that is later transformed into active triiodothyronine (T3).
Thyroxine and triiodothyronine are two major hormones released into the bloodstream by the thyroid gland. Thyroid hormones stimulate all cells and regulate biological processes like metabolic activity, development, reproduction, and growth.
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