long noncoding RNA SNHG5 induces the NF-KB pathway by regulating mir-181c-5p/cbx4 axis to promote the progression of non-small cell lung cancer because Low miR-181c-5p and high SNHG5 and CBX4 levels were found in NSCLC cells or tissues.
The Restoration of miR-181c-5p and RNA SNHG5 restrained the progression of NSCLC cells or tissues and inactivated the NF-KB pathway.
Therefore, RNA SNHG5 regulated the interaction between miR-181c-5p and CBX4, gradually there is termination of SNHG5 which hold back the non-small cell lung cancer or tumor growth.
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You are working on a project to study Darwinian Evolution , and you are trying to identify the conditions for your experiment that would help you illustrate the arguments of Darwin's Theory of Evolution (Descent with Modification and Evolution by Natural Selection )All of the following conditions would help you with this project EXCEPT
A Having an easily controlled environment that you can introduce certain selective pressures that mimic natural conditions in the wild.
B) A model organism that is haploid , or only has one set of chromosomes , which makes it easier to see the effect of changes in the genotype (or genetics ) on changes in the phenotype (or physical and biochemical characteristics ) of the organism
C) A CRISPR - Cas9 based genetic system that allows you to introduce specific mutations into the germ line genome (gametic genome ) of your model organism .
D) Using a bacterial species that is known to swap pieces of DNA between individuals , allowing for the spread of certain characteristics throughout the population without having to reproduce and pass these traits on to offspring .
All of the following conditions would help you with this project EXCEPT the one that uses a bacterial species that is known to exchange pieces of DNA between individuals, as this genetic transmission would impair the visualization of phenotypic adaptations in the environment.
D) Using a bacterial species that is known to exchange pieces of DNA between individuals, allowing certain traits to spread throughout the population without having to reproduce and pass those traits on to offspring.What is meant by Darwinian evolution?Darwin defined evolution as "descent with modification," the idea that species change over time, give rise to new species, and share a common ancestor. The mechanism that Darwin proposed for evolution is natural selection.
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which condition occurs in the presence of cellular damage? group of answer choices cells shrink. atp production increases. osmotic pressure decreases. sodium and water move into the cell.
Sodium and water move into the cell in the presence of cellular damage.
Water and sodium ions are highly required by damaged cells in order to heal or rid them of various conditions.
Cellular Damage- Cell damage, is any type of stress that a cell experiences as a result of both internal and external environmental changes. This can be caused by a variety of things, such as physical, chemical, viral, biological, dietary, or immunological variables.
Immunological Variables- The immune system recognizes substances that contain antigens and makes an effort to get rid of them. Antigens are proteins that are found in the cells of our body. These include the subgroup of HLA antigens. Certain antigens grow familiar to our immune system, and it usually does not react negatively to them.
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carbon dioxide removed by forests and stored in the biomass of trees helps reduce the impacts of climate change. this an an example of a
Carbon dioxide removed by forests and stored in the biomass of trees helps reduce the impacts of climate change this is an example of a Carbon sequestration
What is Carbon sequestration ?The most often produced greenhouse gas is carbon dioxide. The technique of removing and storing carbon dioxide from the atmosphere is known as carbon sequestration. It is one strategy for lowering atmospheric carbon dioxide levels in an effort to slow down the rate of global climate change.
Sequestering carbon in its natural sinks, such as forests, grasslands, and soil, is the most effective approach to remove it. Therefore, a rapid increase in the ability of natural carbon sinks to absorb atmospheric carbon is necessary to achieve the 1.5°C target. Additionally, this is necessary to stop desertification.Learn more about Carbon sequestration here:
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Why did the National Organization for Women advocate for abortion prior to
its legalization in 1973?
OA. Many prominent feminists were unable to participate fully in
politics because they had children.
B. Feminist leaders felt that reproductive choice was an essential
element of women's equality.
C. No safe or effective birth control method was available, so
feminists felt abortion was an unfortunate necessity.
D. At the time, childbirth still carried a high risk of mortality for the
mother, with a death rate of about 10 percent.
Answer:Since our founding in 1966, NOW's purpose is to take action through intersectional grassroots activism to promote feminist ideals, lead societal change, eliminate discrimination, and achieve and protect the equal rights of all women and girls in all aspects of social, political, and economic life.
Explanation:
irf4 transcription factor- dependent cd11b dendritic cells in human and mouse control mucosal il-17 cytokine responses.
The correct answer it will aid in the transcription of mouse in vivo findings to advance DC-based clinical therapies.
Although mouse and human dendritic cells (DCs) are made up of functionally distinct subsets, precise interspecies correlation is currently lacking. In this study, we discovered that murine lung and gut lamina propria CD11b+ DC populations were divided into two subsets: FLT3- and IRF4-dependent CD24+CD64 DCs and contaminating CSF-1R-dependent CD24CD64+ macrophages. CD24+CD11b+ DC loss inhibited CD4+ T cell-mediated interleukin-17 (IL-17) production in the steady state and after Aspergillus fumigatus challenge. Human CD1c+ DCs, which are the equivalent of murine CD24+CD11b+ DCs, expressed IRF4, secreted IL-23, and induced T helper 17 cell responses. Our findings revealed heterogeneity in the mouse CD11b+ DC compartment and identified IRF4-expressing DCs in mucosal tissues that are specialised in instructing IL-17 responses in both mice and humans.
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innate immune suppression by sars-cov-2 mrna vaccinations: the role of g-quadruplexes, exosomes, and micrornas
The SARS-CoV-2 mRNA vaccines were released on the market in response to the Covid-19 public health emergencies.
How innate immunity was suppressed by SARS-CoV2 vaccine?The SARS-CoV-2 spike protein is synthesized continuously by mRNA vaccines.The DNA repair pathways are hampered by the spike protein, which is neurotoxic.Impairment of innate immunity arises from suppressing type I interferon responses.The mRNA vaccinations may raise the chance of developing cancer and infectious illnesses.Codon optimization leads to the production of G-rich mRNA, which has unanticipated, complex effects.Learn more about the vaccination with the help of the given link:
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Which of the following represents arrow C? ( Look at photo )
A. Carbon Dioxide
B. Glucose
C. Oxygen
D. Blood Vessel (capillary)
Answer: The right answer is B
Explanation:
explain how the evolutionary theories after darwin affected (or did not affect) the fundamental principles of biological evolution.
History is occasionally altered by thoughts. This category includes Charles Darwin's idea of evolution by natural selection, making Darwin one of the most significant philosophers of the modern era. He contributed to a change in how people perceived the natural world and how humans fit within it.
What is Darwin's theory of evolution ?The English naturalist Charles Darwin and others created the Darwinism theory of biological evolution, which claims that all species of organisms arise and develop through the natural selection of minute, inherited variations that improve the individual's capacity for competition, survival, and reproduction.
In his 1859 book "On the Origin of Species" (opens in new tab), Charles Darwin originally proposed the Theory of Evolution by Natural Selection.Learn more about Evolution here:
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the external muscle layer of the pharynx consists of three muscles composed of voluntary skeletal muscle.
The pharyngeal external wall is made up of four muscles: the superior pharyngeal constrictor, the middle pharyngeal constrictor, the inferior pharyngeal constrictor, and the stylopharyngeus. The three paired inner pharynx muscles work together to elevate the larynx, shorten the pharynx, and act during swallowing and speaking.
The stylopharyngeus, palatopharyngeus, and salpingopharyngeus are the names of these muscles. The pharyngeal muscles, which consist of an outer circular layer and an interior longitudinal layer, form the lumen of the pharynx. The superior, middle, and inferior pharyngeal constrictor muscles make up the outer circular layer. The pharynx connects the nasal passages to the oesophagus and larynx.
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inhibition of post-synaptic kv7/kcnq/m channels facilitates long-term potentiation in the hippocampus
The development of synaptic plasticity and improved cognitive performance are facilitated by the activation of muscarinic acetylcholine receptors (mAChR). M(1) mAChR on CA1 pyramidal cells in the hippocampus inhibits both voltage-activated Kv7 potassium channels and small conductance Ca(2+)-activated KCa2 potassium channels.
What is Synapse ?The places of contact between neurons known as synapses are where information is transferred from one neuron to the next. Presynaptic neuron, synaptic cleft, and postsynaptic neuron are the three components of synapses, which most frequently occur between axons and dendrites.
I = communicating axosomatic synapses, II = communicating axodendritic synapses, and III = communicating axoaxonic synapses are the three types we identified. They could be referred to as "complex communicating synapses" when three neurons get involved in the synaptic interaction.Learn more about Synapse here:
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What is the purpose of the media?
OA. To convey information
OB. To manipulate the audience
OC. To control people's lives
D. To entertain large groups of people
Answer:
To entertain large groups of peopleExplanation:
The purpose of the media to entertain large groups of people
Which group of organisms contains no representative species that are known to fix nitrogen?.
Answer:
Eukaryotes is the correct answer.
Answer:
eukaryotes is the correct answer
Give the translation for the mRNA and then use the codon table to get the amino acids. You only need to write the first three letters of the amino acids in the answer.
DNA - TAC - AGG - GTC - GCA - CAT - GGG
mRNA -
AA's -
true or false. for this experiment, aeromonas were introduced before vibrio into the larval zebrafish gut.
This is true since Aeromonas population appeared constant over the first three days whereas Vibrio population had not yet established itself.
When Vibrio is absent, Aeromonas can persist in the stomach of zebrafish larvae.
What illness can Aeromonas contribute to?A Gram-negative, rod-shaped, motile bacteria belonging to the Vibrionaceae family is called Aeromonas hydrophila. In humans, it frequently affects immunocompromised hosts and is responsible for a wide range of diseases, including septicemia, meningitis, and endocarditis. Aeromonas spp. have also been epidemiologically linked to traveler's diarrhea.What kinds of Aeromonas are examples?Aeromonas hydrophila, Aeromonas veronii biovar sobria, Aeromonas schubertii, and Aeromonas caviae are only a few of the species that have been linked to necrotizing fasciitis cases. Severe infections are also linked to Aeromonas dhakensis.What illness can Aeromonas contribute to?
A Gram-negative, rod-shaped, motile bacteria belonging to the Vibrionaceae family is called Aeromonas hydrophila. It results in a variety of infections.
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A researcher working in the field of evolution has decided that they would like to develop a species of pig that can fly. Out of the following issues, what is the biggest one that will impede the progress of this project?
A) Most pig species require lots of resources to maintain , making it difficult to care for the animals.
B) Pig genomes have many active retroviral elements in the genome that introduce many mutations every generation
. C) There are no pig species that have individuals with any characteristics that we associate with flight .
D) Designing an environment that would select for pigs that could fly or select against pigs that could not fly .
Of the issues, the biggest factor that will impede the progress of this project is There are no swine species that have individuals with characteristics that we associate with flight.
C) There are no swine species that have individuals with characteristics that we associate with flight.What is genetic improvement of an example?Genetic improvement is the process of intentionally selecting or modifying the genetic material of a living being to obtain individuals with characteristics of interest.
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F. Thomas Edison developed______in 1891 the first motion picture system
F. Thomas Edison developed Kinetograph in 1891 the first motion picture system.
Kinetograph is simple a camera through which a series of images can be clicked of moving objects. These images are observed or viewed using another apparatus called the kinetoscope. The images clicked are viewed through a magnifying glass in the kinetoscope.
Motion picture system is any apparatus that can click pictures of moving objects. These pictures are clicked in a series that result in the formation of a film or video. The motion picture film usually contains 24 frames in one second. The motion pictures can be classified into three categories: camera, intermediate and laboratory, and print films.
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An investigator wants to test for the presence of simple sugars in a sample. She adds reagent to her sample and also to a sample of distilled water. What reagent should she have added?.
An investigator wants to test for the presence of simple sugars in a sample. She adds reagents to her sample and also to a sample of distilled water. She should use Benedict's reagent.
What do you mean by Benedict reagent?
Benedict's reagent (also known as Benedict's qualitative solution or Benedict's solution) is a chemical reagent and complex mixture of sodium carbonate, sodium citrate, and copper(II) sulfate pentahydrate.
It is frequently used in place of Fehling's solution to detect the presence of reducing sugars. The presence of other reducing substances also yields a positive result. Benedict's tests are those that use this reagent. A positive Benedict's reagent test results in a color change from clear blue to brick-red with a precipitate.
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True or False: In order for physical evidence to be used effectively for aiding an investigator, it must first be photographed and tagged as evidence and turned over to the officer in charge of the crime scene.
The answer would be false
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after a skeletal muscle fiber is treated with a membrane permeable drug that speeds up the action of the sr ca 2-atpase, how would the first twitch differ? 1 point the twitch would last the same amount of time the twitch would be shorter the twitch would produce more tension the twitch would last longer
The twitch would be shorter .
What is membrane permeability?
The passive diffusion rate of penetrated molecules through the biomembrane can be used to quantify a membrane's permeability. It is widely acknowledged that a single molecule's permeability is primarily influenced by its size, polarity, charge number, and molar mass.
Muscle goes through two stages: moderation and decrease. Once no reduction will occur upon inspiration, reduction is followed by an obstinate section. When the sr ca2+ ATPases are active and moving calcium back to the sarcoplasmic reticulum, this is the portion that occurs. The forces then start to decrease. The condition is referred to as an amalgamate tetanus if the inspiration are frequent enough to eliminate the relief quantity. The biological period is shorter and the amalgamate tetanus would be extended more quickly with faster sr ca2+ drives effort.
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the medium ground finch lives on the galapagos islands. birds with beaks of all sizes were originally part of this population. the finches are seed eaters. the types of food available for them to eat depends on the weather. during wet years, there is a large variety of food. during dry years, there is less food, and large, tough seeds are more abundant than small seeds.
After the long drought, the researchers noticed that the certain differences in the population of the medium the ground finches living compared to those who lived before the drought are. A. They had smaller wings. B. had larger wings. C. were a new species. D. They had larger beaks
The Darwin's finches are the group of about 18 species of passerine the birds. They are well known for their remarkable diversity in the beak form and the function. They are often classified as the subfamily of Geospizinae or the tribe Geospizini. They belong to the tanager family and they are not closely related to the true finches.
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Answer: They had larger beaks.
Explanation:
Discuss the circulatory system of an insect
Explanation:
Insects have an open circulatory system which lacks veins and arteries. The hemolymph flows freely through the body lubricating tissues and transporting wastes and nutrients. The hemolymph present in insects helps the heart pump it throughout its circulatory system.
Why is it theorized that the asteroids die
not merge to form a planet?
Answer:
there's not enough total mass in the belt to form a planet. The belt contains only about 4 percent of the Moon's mass in asteroids
Explanation:
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which step in the scientific method do you graph results classified information and make calculation?
According to the research, the correct option is Data analysis. It is the step in the scientific method where you graph results classified information and make calculation.
What is scientific method?It is the series of steps that must be followed to obtain valid knowledge from a scientific point of view, using reliable instruments for this.
Among the necessary steps that make up the scientific method are:
ObservationFormulate a hypothesisExperimentationData analysisPresentation of the scientific theoryIn this sense, Data analysis is the stage that uses graphs for the representation of data, generally numerical and make calculation, with a relationship between them, which facilitates the interpretation of the results.
Therefore, we can conclude that according to the research, the correct option is Data analysis. It is the step in the scientific method where you graph results classified information and make calculation.
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nsulation particles can get trapped in the crimp joint and form the basis of a defective
Insulation particles can get trapped in the crimp joint and form the basis of a defective termination
What is conductor termination?The work done at the end of a wire to enable it to connect to a device is known as a wire termination (connector, switch, terminal, etc.). In the aircraft sector, there are numerous termination kinds, but they can be divided into two major groups: crimp and solder.
When a contact or terminal is needed by the device, a crimp termination is carried out. The wire insulation is removed, and a crimp tool is used to join the contact or termination to the wire. The contact or termination is crimped onto the wire conductor using the tool. The aviation wiring harnesses and circuit breaker panels that Interconnect manufactures for various aircraft most frequently use this form of termination.
When the wire conductors are connected to the device directly a solder termination, is carried out. In order to connect the wire to the device, it is necessary to remove the insulation from the wire and apply flux and solder.
What is the basis of defective termination?The insulation might be fractured, scratched, or pierced by poor stripping. As a result, the conductors' resistance to moisture and abrasion may decrease and changes in dielectric strength may result. Insulation fragments frequently become stuck in solder and crimp junctions.
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awad k, young s, aswath p, varanasi v: interfacial adhesion and surface bioactivity of anodized titanium modified with sion and sionp surface coatings. surf interfaces, 28:101645, 2022.
Interfacial adhesion and surface bioactivity of anodized titanium modified with SiON and SiONP surface coatings, The statement is correct.
what is adhesion ?Adhesion is a type of attraction between two dissimilar phases, the theory of adhesion can be up two types mechanical interlocking and physical and chemical bonding and it is a combination of three methods.
Mechanical interlocking means when two dissimilar phases interact with one another by mechanical forces, requires a rough surface where the other material can enter.
Physical bonding includes van der Waals forces and the strength is rather weak and unable to contribute that much bonding strength.
Chemical bonding consist of covalent, ionic and metallic bonding which are more stronger than physical bonds and are responsible for cohesive forces.
chemical bonding between two dissimilar materials is more complicated due to the presence of few available bonding sites.
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How can biology be studied at different scales, or levels?
Answer:
Typical levels of organization that one finds in the literature include the atomic, molecular, cellular, tissue, organ, organismal, group, population, community, ecosystem, landscape, and biosphere levels.
Explanation:
Typical levels of organization that one finds in the literature include the atomic, molecular, cellular, tissue, organ, organismal, group, population, community, ecosystem, landscape, and biosphere levels.
1) What did you notice about the letter e when you increased in magnification from the 4x to the 10x and then to the 40x:
a) Did the size (magnification) increase or decrease?
b) Could you see more of the entire letter or less?
(Subject science)
Answer:i can help but ur question is missing something give me the complete question and i will answer!!
Explanation:
the maximum size of a cell is limited by . view available hint(s)for part a the maximum size of a cell is limited by . its need for enough surface area to make exchanges with its environment the number of organelles that can be packed inside the materials needed to build it the amount of flexibility it needs to be able to move
The organism's cells are constrained by their varying shapes and sizes. Due to the need for surface area to exchange gases, the size distribution of the cell has been limited. Thus, option a is correct.
What is a cell?The smallest unit of an organization that is essential for life is known as a cell. The different cells' varying sizes and shapes enable them to carry out various functions and activities.
The size distribution of the cell has been influenced by the cell's requirement for a cell surface area and volume in order for the exchange of gases to actually happen.
Therefore, option a. the cell size is influenced by surface area and gas exchange.
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What is the largest structure people have put into space?(1 point)
Answer:
The I.S.S(International Space Station)
Explanation:
This was the largest structure humans put into space. It was built between 1998 and 2011, and the space station is still planning missions to this very day.
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Why would CH not form as a result of carbon’s interactions with other elements?
CH would not be formed as a result of carbon’s interactions with other elements and this is due to carbon's 4 valence electrons. Carbon would need four more electrons to fill its outer shell.
Why does carbon need four electrons?
Carbon has 6 atomic numbers and an electron configuration of 1s2 2s2 2p2. Found in all living organisms and organic compounds, carbon atom can form covalent bonds to as many as four other atoms and for carbon to achieve stability, it must find four more electrons to fill its second shell.
In summary, carbon would form covalent bonds with other elements in such a way that electrons would fill its outer shell, making a total of eight electrons in its outer shell thereby satisfying the octet rule.
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Carbon’s ability to form bonds with four other atoms goes back to its number and configuration of electrons. Carbon has an atomic number of six (meaning six protons, and six electrons as well in a neutral atom), so the first two electrons fill the inner shell and the remaining four are left in the second shell, which is the valence (outermost) shell. To achieve stability, carbon must find four more electrons to fill its outer shell, giving a total of eight and satisfying the octet rule
valence (outermost) shell. To achieve stability, carbon must find four more electrons to fill its outer shell, giving a total of eight and satisfying the octet rule